Prozac

• Other medicines:
• Celexa
• Desyrel
• Paxil
• Reglan
• Zyprexa
• Seroquel

There is not a guarantee to happiness. But the man would be no man, or at least a prescription if he do not like to have a guarantee. Viewed in that it is not surprising that antidepressants such as Prozac (drug fluoxetine in Germany as a Prozac prescription required available) as a so-called 'happiness pills' have economy for years.

How strong is the collective desire for happiness, can be read from the immense success of antidepressant Prozac. 1987 come in the United States on the market, it was praised because of its low side effects as a panacea. Since the introduction of more than 20 million Americans consumed it, throughout the world, there are now approximately 40 million consumers. Sold in more than 100 countries now: Prozac, a hit of first.
Not every consumer is depressed

The height of the figures is thus concluded that mainly general practitioners are quick to prescribe fluoxetine, although many patients strictly speaking do not suffer from a real depression against depression. In the United States, where the drugs are available, many people of Prozac, which would otherwise most likely never take an antidepressant swallow. Bad on it? No problem: just a Prozac pill, and it is again good spirits. In the always-smile-I ´ m doing fine company United States is apparently not misfits grumpiness.

At the beginning of the 20th century, as many of today's pharmaceutical began their ascent, was still, for people to produce resources for healing. As the discoverers of insulin in 1923 were awarded the Nobel Prize, they still voluntarily shared this with colleagues who were significantly been involved in the development, but by the Nobel Committee ignored have been. And they sold their precious patent for the symbolic price of one dollar to the University of Toronto.
Since the 1980s it comes now to invent "Blockbuster", which bring within the shortest time billion sales. Virapen: "A blockbuster is a pill time sold much more than just." "A blockbuster is a pill of the disease, which is to be cured, is completely secondary." Quite simply, because sufferers are in a "relatively small market". "Can imagine, you could sell pills also those, who are not sick!" Only then, you have entered a new dimension of marketing. This is the quality of blockbusters. And Fluoxetine should play this role. "This was more by chance, because it was not really suitable for this role."
Fluoxetine is an agent that prevent the resumption of the Messenger substance serotonin in the brain and thus turns on the controller of the balance of serotonin and allegedly restores the balanced, ideal State. It should serve as an antidepressant.

Now it is known that the serotonin levels in the brain can measure not be; and studies have also shown happiness or sadness a person not to depend on biochemical processes in his brain. Trials of fluoxetine but showed an interesting side effect: some of the subjects had thus lost weight - an aspect that the heads of corporations believed to be much more lucrative.
Thickness are - as they real or conceited so en masse there - an outstanding market. It was only bad that we more extensive research and testing needed, seeking approval as to achieve drug reducing solution. "Eli Lilly but had it in a hurry", noticed Virapen. "Every lost day was the new wonder drugs not on the market, cost money."
So it was decided to seek the approval of the active substance fluoxetine first as an antidepressant. "Because once approved, it is easier to later extend the approval to other applications." "This is a very common, important trick of the pharmaceutical industry can watch again and again."

The way of medicine for a market runs on certain stations: assesses the initial effects and side effects of the active substance in the laboratory, then on animals. After that is the human "Guinea pig", mostly in hospitals. Such testing is called in the jargon of "Protocols". Runs a protocol not as hoped, it cancels it. Since fatally broken tests - so "protocols" - and their results must not be given to the regulatory authorities. "But why cancels one a series of experiments?" "Because there are difficulties, because too many patients unable to tolerate the drug, which kill or for other health reasons not further participate trying", writes Virapen. "Just this information important for regulatory authorities and patients in PES, disappear in the cabinets of the Pharmamanager."

In rare cases: Disorders of fluid and salt budget with confusion, seizures, edema (swelling due to accumulation of aqueous fluid in the tissue columns, such as the skin and mucous membranes).

On the occurrence of side effects, of which you suspect a connection with the use of Prozac, please inform your doctor.

General notes

What is also to consider?
Although there are so far no reports of impaired responsiveness by Prozac, caution while operating is machines and the driving of motor vehicles.

Alcohol is to avoid during treatment with Prozac.

In diabetes patients therapy with Prozac may require a dosage adjustment of insulin and/or the oral Antidiabetikums. Diabetics should speak with their doctor about Prozac therapy because of this.

Keep unreachable for children.

Store at room temperature (15-25 ° C).

No longer use after the deadline.

Your doctor or pharmacist, who has the detailed information provide the further information.

Composition

Capsules

1 Capsule Prozac contains Fluoxetinhydrochlorid to 20 mg of fluoxetine, dye E 131, as well as other auxiliary materials.

Clinical practice as a counterargument

Dieter Ebert is to bear in mind that the result could be related with the preselection of the patients in the studies: the Hamilton value alone is not a sufficient criterion for depression - and people who really suffered from clinical depression with the corresponding biochemical changes in the brain, SSRIs could not just also help. A disease-valued depression can go hand in hand on the other hand even with a relatively low value on the Hamilton scale. The result of the study is therefore problematic, because "it suggests that in mild depression drug and placebo as well act". In contrast, but refer to clinical practice.

The pharmaceutical companies that produce appropriate medication, responded as expected with rejection to the study. The manufacturer Eli Lilly issued a statement that references it, that the own product fluoxetine (the active ingredient of Prozac) "since its discovery in 1972 one of the most analysed of the world" is. "Extensive scientific and medical experiences have demonstrated that Fluoxetine is an effective antidepressant". A spokesman for GlaxoSmithKline, the maker of Seroxat, also referred to clinical practice, which have yielded "very positive" results. Also, "only a small subset of the entire available data" has been examined. You should not use the study to "raise unnecessary concern among patients".

The largest manufacturers of SSRI - Eli Lilly, GlaxoSmithKline, Wyeth and Pfizer - are thus after four years again under great pressure. In 2004, previously unpublished data were public, no measurable effectiveness occupied, but a link between the modern, supposedly low-side effects paxil drug paroxetine and an increased risk of suicide in children and adolescents. Also at that time, the outrage was great, the measures however fell from modest: manufacturers were to have to install warnings on the packets of the drug. The dreaded sales drop for the drug Group remained out, because as recently psychologists have found in the archives of General Psychiatry, the warnings have led to more caution, but not to give up the popular happiness pills.

If now, in the light of new studies something understanding changes? Hardly, because antidepressants breastfeed apparently an unruly need for help. Alone, the active ingredient fluoxetine (known as Prozac or Prozac) was already occupied by 45 million people worldwide. The side effects range from nausea on diarrhea to sexual dysfunction - but the people swallow this stuff. And not only in the United States, where Prozac is prescribed most often and five percent of all prescriptions affect children, the use of antidepressants is unstoppable: also in Germany reached according to drug report alone for fluoxetine the brand of half a million, and rising prescription daily doses.